in FSGS and Minimal Change Disease
Analytics to support research questions
Researchers have found that in some patients when two markers in the urine are at higher levels, this can indicate that a protein called TNF is an component in causing FSGS and Minimal Change Disease to be active.
In this study, we are looking to see if a medication called Humira will block the TNF pathway, causing the levels of the two urine markers to decrease.
Who may be eligible?
Willing to give urine sample to evaluate TNF activation for screening
FSGS or Minimal Change Disease on biopsy
6-70 years of age
GFR > 45 ml/min
Urine protein ≥1.5 g/g creatinine at screening
For more information:
Call KRN at (734) 232-4830 or toll free (844) 618-2478
Email at KidneyResearchNet@med.umich.edu